Acomplia Diet Pill Now Available

Acomplia, (Rimonabant) the new wonder diet pill, which was approved for use in the UK last year, is now available online. Rimonabant can be purchased online with worldwide shipping offered too. Check out the Rimonabant page at 123 Diet Pills 4 Weight Loss to order.

Acomplia / Rimonabant - Technical Information

Acomplia was recently approved in the UK as a controlled medication and is under application in the US. The active ingredient in Acomplia is rimonabant, which is a CB1 endocannabinoid receptor antagonist.
(The endocannabinoid system is in the part of the brain that regulates metabolism, energy levels and appetite).

Rimonabant prevents the endogenous cannabinoid binding to CB1 receptors in nerve cells. These CB1 receptors, when activated, stimulate appetite. Hence this drug blocks the activation of these CB1 receptors and thus reduces appetite.

The CB1 endocannabinoid receptors are also involved in the mechanism of other addictions such as smoking, and it may be in time that this drug is approved as a treatment for addictions. Certainly, the effect on the endocannabinoid receptors has a benefical effect on blood glucose and lipid levels - a more beneficial effect than would be expected from weight loss alone.

Side Effects

All drugs have side effects, and Acomplia is no exception. Some of the side effects are beneficial - such as the altered blood lipid profile. However, there are other known side effects that may influence whether or not you continue to take the drug.
Nausea and vomitting
Nausea, vomitting and other gastrointestinal disorders were relatively common side effects of taking Acomplia.Disorders of the nervous system
This category includes headaches, faintness and feeling dizzy.Psychiatric disorders
Including mood swings, anxiety, depression, irritability, sleep disorders and other similar disorders. If you already have a history of mental health disorders, it would be highly adviseable to mention this to your doctor before obtaining this drug. The table attached is an indication of the relevant frequency of side effects when taking 20mg Acomplia daily, compared to the placebo.
(Source: one year data from RIO-LIPIDS, RIO-Europe and RIO-NORTH AMERICA)

Contraindications

Acomplia should not be taken, or should be taken only under exceptional circumstances under your doctor's direct guidance, in the following circumstances:

   1. Anyone who exhibits hypersensitivity or an allergic reaction to the drug (it should never be used in these circumstances).
   2. Anyone with an impaired liver function. The effects of Acomplia have not been studied in patients with liver damage.
   3. Anyone with impaired kidney function. It should never be used in patients with a severly limited kidney function.
   4. Anyone over the age of 75. There is no data currently available to establish safety in this age group.
   5. Any children under the age of 18 - there is currently a lack of data on efficacy and safety for this age group.
   6. Pregnant or lactating women - safety in these groups has not been established. Indeed, current data in rats shows possible damage to the developing foetus and an inhibited sucking reflex in young rats.
   7. There is little data on the safety of Acomplia in patients suffering from epilepsy and it should be prescribed with caution in these instances.
   8. The Acomplia tablet contains lactose and should therefore not be prescribed to patients with a lactose intolerance.
   9. It should only be used with caution in combination with CYP3A4 inhibitors, such as ketocinazole, ritonavir, clarthromycin and related drugs.
10. It should not be prescribed to patients with an uncontrolled psychiatric condition, and is not recommended for use with antidepressants as there is a lack of data on the safety in these circumstances.

We make no claims as to the completeness of this list - there may well be other contraindications to the prescription of Acomplia.